Deep Brain Stimulation, physical activity, and exercise as viable interventions for the motor symptoms of Parkinson's disease patients

Leemhuis, Marlin (2021) Deep Brain Stimulation, physical activity, and exercise as viable interventions for the motor symptoms of Parkinson's disease patients. Bachelor's Thesis, Biology.

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Abstract

Ageing is the main cause of Parkinson’s disease. The quality of life of the patients decreases, among others because of the displayed motor symptoms. The displayed symptoms are not consistent for all individuals leading to irregular treatment patterns. To improve the health-related quality of life different interventions, pharmacological as well as non-pharmacological, are applicable. For that reason, this research paper focuses on Deep Brain Stimulation, exercise, and physical activity specifically as interventions for motor symptoms of Parkinson's disease. Deep Brain Stimulation is the stimulation of deep brain nuclei with the use of electrodes. Performing this surgery on the subthalamic nucleus and the globus pallidus internus illustrates the improvement of the overall motor function and thereby an improvement in the quality of life. Stimulation of the globus pallidus internus indicates improvements for the motor symptom dyskinesia in particular. The concept of exercise falls within the definition of physical activity. It is important to prevent adjusting to a sedentary lifestyle since this contributes to a decreased quality of life. Neuroinflammation can be repressed by exercise and treadmill training is applicable as an intervention for the disruption of gait. Altogether, the mentioned interventions can be applied to diminish the motor symptoms of Parkinson's patients improving the health-related quality of life.

Item Type:	Thesis (Bachelor's Thesis)
Supervisor name:	Zee, E.A. van der
Degree programme:	Biology
Thesis type:	Bachelor's Thesis
Language:	English
Date Deposited:	13 Oct 2022 12:42
Last Modified:	13 Oct 2022 12:42
URI:	https://fse.studenttheses.ub.rug.nl/id/eprint/24988

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