Remmelts, Maximiliaan, M.T. (2021) Effect of nano- and microplastics on the human immune system and their influence on inflammatory bowel disease. Bachelor's Thesis, Biology.
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Abstract
In this paper the effects of micro- and nanoplastics are researched, specifically their effect on the immune system, microbiome, and the incidence of inflammatory bowel disease. Consumption of plastic particles differs per person and can easily be reduced after awareness. Plastic particles elicit an inflammatory response with mainly IL-1α, IL-6, IL-8 and TNF-α. Furthermore, a reduction of mucin production and increase in intestinal epithelial cell permeability is observed. Thus, plastics can possibly cause the leaky gut syndrome. Plastic particles also cause dysbiosis by reducing commensals and increasing pathogenic bacteria. Therefore, it is expected that high micro- and nanoplastic consumption can trigger and aggravate inflammatory bowel disease.
| Item Type: | Thesis (Bachelor's Thesis) |
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| Supervisor name: | Melgert, B.N. and Olinga, P. |
| Degree programme: | Biology |
| Thesis type: | Bachelor's Thesis |
| Language: | English |
| Date Deposited: | 07 Jul 2021 10:31 |
| Last Modified: | 07 Jul 2021 10:31 |
| URI: | https://fse.studenttheses.ub.rug.nl/id/eprint/25026 |
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