Wageningen, Jeroen van (2021) Applications and Future Potential of Directed Evolution for Combatting Antifungal Resistance. Bachelor's Thesis, Life Science and Technology.
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Abstract
This review paper will explore different ways in which directed evolution can be used to combat the observed increase in antifungal resistance. In order to do this comprehensively, I describe the fungal kingdom, characteristics of different antifungal groups and the rise of antifungal resistance. After sketching the current fungal landscape, I will introduce directed evolution. In addition to exploring the general concept of directed evolution, its different methods, strengths and shortcomings will be discussed. Within the context of antimicrobials, examples of previous applications of directed evolution will be examined. Additionally, the potential for future uses of directed evolution within this field will be explored extensively. Conclusively, this review paper will explore the previous applications and future potential uses of directed evolution within the context of combatting antifungal resistance.
| Item Type: | Thesis (Bachelor's Thesis) |
|---|---|
| Supervisor name: | Billerbeck, S.K. |
| Degree programme: | Life Science and Technology |
| Thesis type: | Bachelor's Thesis |
| Language: | English |
| Date Deposited: | 23 Jul 2021 08:17 |
| Last Modified: | 23 Jul 2021 08:17 |
| URI: | https://fse.studenttheses.ub.rug.nl/id/eprint/25409 |
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