Fecal Microbial Transplantation in Treatment of Anorexia Nervosa

Neutelings, E. (2021) Fecal Microbial Transplantation in Treatment of Anorexia Nervosa. Bachelor's Thesis, Life Science and Technology.

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Abstract

Anorexia Nervosa (AN) is a mental illness marked by a very low body weight and extreme dieting of patients. The severity of this disease is manifested in its high mortality rates. The current treatment for AN includes a restoration of weight and nutrition, and psychotherapy such as family and group therapy or behavioural therapy. Because of the high relapse and drop-out rates for AN treatment, new insights are needed. Physiological complications are an explanation for the high mortality rates and if treated might be a good addition to AN treatment. A recently shown important medical complication in AN patients are problems in the gastrointestinal (GI) tract. GI complications like celiac disease, irritable bowel syndrome and inflammatory bowel disease can make it difficult for AN patients to start eating on top of their mental problems. These GI diseases are associated with a dysbiosis of the intestinal microbiota. Even after weight restoration the gut microbiota is still affected in AN patients and might cause problems in long-term rehabilitation. For treating the microbiota fecal microbial transplantation (FMT) is suggested to be a favorable treatment for restoring a normal gut microbiota. For this reason, there might be a possible positive effect of FMT as an addition to the present treatment for AN. For future research, the positive effect of FMT on the gut-brain axis in AN patients can also be examined because of the importance of a healthy gut on the functioning of the

Item Type:	Thesis (Bachelor's Thesis)
Supervisor name:	Scheurink, A.J.W.
Degree programme:	Life Science and Technology
Thesis type:	Bachelor's Thesis
Language:	English
Date Deposited:	13 Aug 2021 10:55
Last Modified:	13 Aug 2021 10:55
URI:	https://fse.studenttheses.ub.rug.nl/id/eprint/25688

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