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Psilocybin as Treatment for Depression

Vasse, Kris (2021) Psilocybin as Treatment for Depression. Bachelor's Thesis, Biology.

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Abstract

Depression is the main cause of disability worldwide and negatively affects the quality of life. It is characterised by a depressed mood and a lack of pleasure or interest in activities. Antidepressants and psychotherapy are used to treat depression, however, these treatments are still unsatisfactory as they have limited effectiveness and adherence. Treatment-resistant depression is therefore sometimes diagnosed in the patients that do not respond to these established treatments. Fortunately, more options are available to treat depression such as brain stimulation therapy and treatment with psychedelics. Research on the use of psychedelics for the treatment of psychiatric disorders flourished in the 1950s and 1960s. However, in the late 1960s use of psychedelics was associated with the counter-culture movement and the use of psychedelics was banned, which resulted in the arrest of research that involved the use of psychedelics. In the past years, the potential of psychedelic drugs for the use of mental disorders has been rediscovered. Psilocybin is a classic psychedelic that can be found in a variety of fungi, and functions as a 5-HT receptor agonist. Administration can result in intense changes in perception and mystical experiences. Research on the treatment of depression with psilocybin has shown very promising results with a fast onset of psilocybin’s antidepressant effects and relatively few side effects. This thesis investigates whether treatment of psilocybin is better

Item Type: Thesis (Bachelor's Thesis)
Supervisor name: Scheurink, A.J.W.
Degree programme: Biology
Thesis type: Bachelor's Thesis
Language: English
Date Deposited: 31 Aug 2021 13:49
Last Modified: 31 Aug 2021 13:49
URI: https://fse.studenttheses.ub.rug.nl/id/eprint/25887

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