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Positive liposome uptake mechanisms: The effect of different uptake inhibitors on the uptake of positive liposomes

Mulder, Jasper (2022) Positive liposome uptake mechanisms: The effect of different uptake inhibitors on the uptake of positive liposomes. Bachelor's Project, Pharmacy.

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Abstract

The aim is to determine the effect of different uptake mechanism inhibitors on the uptake of zwitterionic liposomes by Hela cells to see how the liposomes are taken up. This was done by performing multiple experiments exposing the inhibitors to Hela cells at different time points. The results do not give a clear picture of the uptake mechanisms of the liposomes due to the observed increase in uptake for two inhibitors. It has been hypothesized the observation could be due to overcompensation by another pathway or an altered stability of the liposomes.

Item Type: Thesis (Bachelor's Project)
Supervisor name: Salvati, A. and Reker-Smit, C.
Degree programme: Pharmacy
Thesis type: Bachelor's Project
Language: English
Date Deposited: 14 Oct 2022 12:59
Last Modified: 14 Oct 2022 12:59
URI: https://fse.studenttheses.ub.rug.nl/id/eprint/27410

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