Eijnden, Jelke van den (2022) Towards synthetic catch bonds: synthesis and binding properties of a hook-shaped electron-rich host. Bachelor's Thesis, Chemistry.
|
Text
bCHEM_2022_VanDenEijndenJJA.pdf Download (3MB) | Preview |
|
![[img]](https://fse.studenttheses.ub.rug.nl/style/images/fileicons/text.png) |
Text
toestemming.pdf Restricted to Registered users only Download (127kB) |
Abstract
A hook-shaped molecule was synthesised in an attempt to act as a π-stacking host with electron deficient guests, before incorporating this system into synthetic catch bonds. The synthesised hook-shaped host consists in two methoxy-substituted anthracene molecules coupled together and bridged to make the structure more rigid upon pulling. Three electron deficient guests were used in this attempt and changes in absorption and steady-state fluorescence were monitored. For all three combinations the absorbance increased significantly while the changes in emission spectra were different for each guest. The dioctyl-bipyridinium guest increased the fluorescence, while the 4,4’-dinitrobiphenyl guest quenched it. For the third guest (perfluorinated biphenyl) no notable change in fluorescence was observed. The changes in absorbance and fluorescence were attributed to the predicted host-guest interaction. However, more insight into the characterisation, interactions and behaviour are required for a better understanding of this host-guest system.
| Item Type: | Thesis (Bachelor's Thesis) |
|---|---|
| Supervisor name: | Kudernac, T. |
| Degree programme: | Chemistry |
| Thesis type: | Bachelor's Thesis |
| Language: | English |
| Date Deposited: | 15 Jul 2022 12:19 |
| Last Modified: | 15 Jul 2022 12:19 |
| URI: | https://fse.studenttheses.ub.rug.nl/id/eprint/27886 |
Actions (login required)
 |
View Item |