Beintema, Tijana Kyra (2022) How Different Parameters of Sleep Can Influence Cognitive Ageing. Bachelor's Thesis, Biology.
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Abstract
Sleep is important for loads of processes such as emotions, memory, information processing and alertness. Certain parameters of sleep such as structure, quality and duration can change with ageing. Also, ageing is associated with cognitive decline. However, it is not known yet whether the age-related sleep changes in elderly affect cognitive decline. So, this thesis aimed to research whether changes in the parameters of sleep influence ageing in terms of cognition. The direct influence of sleep changes on cognitive decline in elderly will be discussed. Also, the indirect effect of sleep changes on cognitive decline in elderly will be discussed. It was found that lowered sleep efficiency, more night-time awakenings, more wake episodes, late-life onset of insomnia, less REM and less NREM sleep are all associated with cognitive decline. The same accounted for self-reported sleep problems, although opposed by one study. Also, people with self-reported sleep problems were more likely to suffer from early cognitive decline. Sleep complaints and poor sleep quality were found to predict cognitive decline. Changes in sleep have also been found to indirectly affect cognition, through inflammation and accumulation of tau and Aβ. Adenosine was found to play a role in the severity of the effect of sleep on cognition. It was also suggested that sleep could indirectly lead to cognitive decline via depression, but this was opposed by a different study.
| Item Type: | Thesis (Bachelor's Thesis) |
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| Supervisor name: | Drion, C.M. and Scheurink, A.J.W. |
| Degree programme: | Biology |
| Thesis type: | Bachelor's Thesis |
| Language: | English |
| Date Deposited: | 09 Aug 2022 11:12 |
| Last Modified: | 09 Aug 2022 11:12 |
| URI: | https://fse.studenttheses.ub.rug.nl/id/eprint/28313 |
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