Kirsten, Lobke (2025) An Injectable Origami-Designed Soft Magnetically Actuated Stent Graft. Bachelor's Thesis, Biomedical Engineering.
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Abstract
Traditional treatments for popliteal artery aneurysms (PAA), such as catheter-delivered stent grafts, pose various challenges, including difficult navigation through complex vessels and potential tissue trauma caused by rigid stent graft materials. To address these limitations, this work investigates a potential alternative approach: an injectable, magnetically actuated soft robotic stent graft. The proposed device integrates origami-inspired folding for compact, needle-based delivery and leverages magnetic actuation for wireless folding, navigation, and deployment. A soft robotic sheet designed according to a 45° Miura-Ori pattern demonstrated trimodal magnetic actuation, i) including partial folding according to its origami pattern, ii) reconfiguration into a helical, cylindrical structure, and iii) swimming-like locomotion. These results indicate the soft robotic sheet’s ability to deploy into a stent-like structure and suggest its possible wireless navigation within vasculature. Additionally, through magnetic actuation and manual assistance, a small-scale 45° Miura-Ori soft robotic sheet was flat-folded into a compact structure, supporting its potential for needle-based delivery. These findings provide foundational insights toward the development of a novel strategy for minimally invasive stent graft delivery.
| Item Type: | Thesis (Bachelor's Thesis) |
|---|---|
| Supervisor name: | Misra, S. |
| Degree programme: | Biomedical Engineering |
| Thesis type: | Bachelor's Thesis |
| Language: | English |
| Date Deposited: | 07 Jul 2025 13:51 |
| Last Modified: | 07 Jul 2025 13:51 |
| URI: | https://fse.studenttheses.ub.rug.nl/id/eprint/35918 |
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