Facilitating inhibition might inhibit facilitation; a mental fatigue study

Ackooij, M. van (2018) Facilitating inhibition might inhibit facilitation; a mental fatigue study. Research Project 1 (minor thesis), Behavioural and Cognitive Neurosciences.

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Abstract

The current study tries to identify changes in centrality of cortical components related to mental fatigue. Participants were subjected to a scanning session lasting two hours, consisting of either four blocks of modified Eriksen flanker task (fatigue) or two blocks of modified Eriksen flanker and two blocks of relaxing nature documentary watching (control). During scanning, both anatomical and functional scanning was performed. Cortical components were obtained through independent component analysis of a temporally concatenated dataset containing the preprocessed functional data of all subjects and sessions. Adjacency matrices of components within subject and session were constructed based on the time series uniquely defined for each component per subject and session. Subsequently, both positive and signed eigenvector centrality were computed and differences in changes in centrality over time between the control and fatigue groups were identified. Five components show significant different in positive centrality changes over time between groups, however, none of these effects survived multiple comparison correction. Signed centrality revealed additional information, but was deemed too unreliable for further analysis in the current study.

Item Type:	Thesis (Research Project 1 (minor thesis))
Degree programme:	Behavioural and Cognitive Neurosciences
Thesis type:	Research Project 1 (minor thesis)
Language:	English
Date Deposited:	15 Feb 2018 08:35
Last Modified:	15 Feb 2018 08:35
URI:	https://fse.studenttheses.ub.rug.nl/id/eprint/16432

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